Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233473 | 0.88 | KMT2A (0.60) | KMT2AMEN1TAS1R3TAS1R1LPAR1 | |
| SCHEMBL8924220 | 0.87 | TAS1R3 (0.54) | KMT2AMEN1TAS1R3TAS1R1LPAR1 | |
| SCHEMBL8768174 | 0.83 | ALDH1A1 (0.56) | KMT2AMEN1TAS1R3TAS1R1LPAR1 | |
| SCHEMBL8767793 | 0.81 | POLB (0.53) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL9111522 | 0.81 | ALDH1A1 (0.54) | KMT2AMEN1TAS1R3TAS1R1LPAR1 | |
| SCHEMBL8926644 | 0.77 | KMT2A (0.64) | KMT2AMEN1LPAR1ALDH1A1MAPT | |
| SCHEMBL9107793 | 0.75 | TAS1R3 (0.47) | KMT2AMEN1TAS1R3TAS1R1LPAR1 | |
| SCHEMBL14345534 | 0.73 | MEN1 (0.58) | KMT2AMEN1LPAR1ALDH1A1MAPT | |
| SCHEMBL8768931 | 0.72 | PPARA (0.52) | ALDH1A1MAPTTSHRHTTGAA | |
| SCHEMBL703369 | 0.70 | TAS1R3 (1.00) | KMT2AMEN1TAS1R3TAS1R1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |