Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924220 | 0.87 | TAS1R3 (0.54) | TAS1R3TAS1R1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8768915 | 0.75 | TSHR (0.42) | ALDH1A1MAPTTSHRPPARAPPARG | |
| SCHEMBL8768817 | 0.75 | MAPT (0.55) | TAS1R3TAS1R1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8768942 | 0.75 | KMT2A (0.57) | TAS1R3TAS1R1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8767887 | 0.75 | PPARA (0.43) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL9111522 | 0.74 | ALDH1A1 (0.54) | TAS1R3TAS1R1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8768980 | 0.72 | PPARA (0.50) | ALDH1A1MAPTTSHRPPARAPPARG | |
| SCHEMBL8925577 | 0.72 | PPARA (0.60) | KMT2AMEN1MAPTTSHRPPARA | |
| SCHEMBL8926604 | 0.71 | POLB (0.56) | KMT2AMEN1MAPTTSHRPPARA | |
| SCHEMBL9233473 | 0.70 | KMT2A (0.60) | TAS1R3TAS1R1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS. | WELLCOME FOUND (GB) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992010468-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-06-25 | — | — | WO | disclosed |