Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066147 | 0.74 | ENPEP (0.60) | ENPEPGMNNALDH1A1LMNATP53 | |
| SCHEMBL28983643 | 0.72 | GMNN (0.39) | ENPEPGMNNALDH1A1LMNATP53 | |
| SCHEMBL5148886 | 0.70 | ENPEP (0.56) | ENPEPGMNNALDH1A1LMNATP53 | |
| SCHEMBL9575743 | 0.70 | TSHR (0.36) | ENPEPTP53TSHRMAPK1 | |
| Potassium Ion SCHEMBL18008001 | 0.69 | ENPEP (0.43) | ENPEPGMNNALDH1A1LMNATP53 | |
| Potassium Ion SCHEMBL28128448 | 0.69 | ENPEP (0.48) | ENPEPGMNNALDH1A1LMNATP53 | |
| SCHEMBL9295797 | 0.68 | ENPEP (0.65) | ENPEPGMNNALDH1A1LMNATP53 | |
| Lithium Ion SCHEMBL28480860 | 0.68 | GMNN (0.41) | ENPEPGMNNALDH1A1LMNATP53 | |
| SCHEMBL28490537 | 0.68 | GMNN (0.46) | ENPEPGMNNALDH1A1LMNATP53 | |
| Potassium Ion SCHEMBL8715930 | 0.67 | KDM4E (0.53) | ENPEPGMNNALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787540-A1 | WASTE TREATMENT CHEMICAL AND WASTE DISPOSAL METHOD | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-08-06 | — | — | EP | disclosed |