Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876803 | 0.84 | RORC (0.36) | SMN1; SMN2RXRAMAPTMEN1KMT2A | |
| SCHEMBL876802 | 0.84 | RORC (0.36) | SMN1; SMN2RXRAMAPTMEN1KMT2A | |
| SCHEMBL873814 | 0.77 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL874582 | 0.70 | LMNA (0.48) | RAB9ALMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28325495 | 0.68 | CYP3A4 (0.38) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL6722425 | 0.66 | LMNA (0.46) | LMNASMN1; SMN2MCL1ALOX5PTGES | |
| SCHEMBL175787 | 0.65 | SNCA (0.59) | CSNK2A2CSNK2A1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL10489918 | 0.65 | KMT2A (0.58) | RAB9ALMNASMN1; SMN2CSNK2A2CSNK2A1 | |
| SCHEMBL8870031 | 0.64 | ANPEP (0.46) | RAB9ASMN1; SMN2CSNK2A2CSNK2A1RXRA | |
| Bicarbonate SCHEMBL6554150 | 0.64 | SNCA (0.58) | CSNK2A2CSNK2A1MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |