Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876803 | 1.00 | RORC (0.36) | RORCMMP2MMP9MAPK1CACNA1D | |
| SCHEMBL877194 | 0.84 | RAB9A (0.35) | MEN1KMT2AMAPTSMN1; SMN2RXRA | |
| SCHEMBL877592 | 0.80 | MMP2 (0.41) | MMP2MMP9 | |
| SCHEMBL875347 | 0.70 | MEN1 (0.36) | MMP2MMP9CACNA1DGAAMEN1 | |
| SCHEMBL4059596 | 0.67 | MMP2 (0.47) | RORCMMP2MMP9MAPK1PPARG | |
| SCHEMBL28325495 | 0.65 | CYP3A4 (0.38) | MAPK1GAAMEN1KMT2ACHRNB2 | |
| SCHEMBL2278952 | 0.64 | MAPK1 (0.54) | MAPK1GAAMEN1KMT2ATP53 | |
| SCHEMBL5356165 | 0.64 | MEN1 (0.46) | CACNA1DGAAMEN1KMT2AMAPT | |
| SCHEMBL6325501 | 0.63 | HSD11B1 (0.47) | RORCMAPK1TP53MAPTSMN1; SMN2 | |
| SCHEMBL6722425 | 0.62 | LMNA (0.46) | MMP2MMP9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |