SCHEMBL8772290

SCHEMBL8772290

CC(C)(C)c1cc(Cc2ccc(O)cc2)c2ccccc2c1O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.45
HSPA5 P11021 2/20 0.44
HMGB1 P09429 1/20 0.40
CXCL12 P48061 1/20 0.40
BCL2 P10415 1/20 0.40
BCL2L1 Q07817 1/20 0.40
ALOX5 P09917 1/20 0.39
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772295 0.87 HSPA5 (0.50) HSPA5HMGB1CXCL12MEN1GAA
SCHEMBL8772332 0.85 HSPA5 (0.42) HSPA5HMGB1CXCL12BCL2BCL2L1
SCHEMBL9817048 0.84 SHBG (0.42) HSPA5HMGB1CXCL12
SCHEMBL9128005 0.80 CA2 (0.42) HSPA5HMGB1CXCL12MEN1GAA
SCHEMBL19039045 0.80 KEAP1 (0.53) KEAP1
SCHEMBL8772275 0.80 HSPA5 (0.47) HSPA5HMGB1CXCL12MEN1GAA
SCHEMBL8772373 0.80 LMNA (0.50) KEAP1HMGB1CXCL12ALOX5
SCHEMBL8762782 0.79 HSPA5 (0.46) HSPA5HMGB1CXCL12MEN1GAA
SCHEMBL8962592 0.78 KEAP1 (0.47) KEAP1HMGB1CXCL12
SCHEMBL8772299 0.78 LMNA (0.45) HSPA5MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed