SCHEMBL8962652

SCHEMBL8962652

CCc1cc(Cc2ccc(C)cc2)c2ccccc2c1O

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.44
CXCL12 P48061 1/20 0.44
CNR2 P34972 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962592 0.89 KEAP1 (0.47) HMGB1CXCL12
SCHEMBL8772297 0.85 HMGB1 (0.58) HMGB1CXCL12
SCHEMBL8772359 0.84 LMNA (0.50) HMGB1CXCL12
SCHEMBL10337449 0.81 GABRA1 (0.48) HMGB1CXCL12
SCHEMBL19039045 0.78 KEAP1 (0.53)
SCHEMBL8963163 0.78 LMNA (0.47) HMGB1CXCL12
SCHEMBL15342325 0.78 LMNA (0.48)
SCHEMBL9490289 0.78 GABRA1 (0.45) HMGB1CXCL12
SCHEMBL8772369 0.78 HSPA5 (0.49) HMGB1CXCL12
SCHEMBL8772360 0.76 HMGB1 (0.56) HMGB1CXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543286-A CONTAINING AN ORGANIC SILVER SALT AND A PYRROLE COMPOUND;HIGH CONTRAST IMAGES CANON KABUSHIKI KAISHA (JP) 1996-08-06 US disclosed
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP disclosed
US-5262295-A Biphenyldihydroxide reducing agent for silver halide emulsion layers CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
EP-0509740-A1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KABUSHIKI KAISHA (JP) 1992-10-21 EP disclosed
EP-0505155-A1 Heat-developable masking layer CANON KABUSHIKI KAISHA (JP) 1992-09-23 EP disclosed