Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772387 | 0.93 | HMOX1 (0.40) | POLBNPC1 | |
| SCHEMBL8440303 | 0.87 | TP53 (0.45) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL8772384 | 0.85 | MAPT (0.42) | — | |
| SCHEMBL8443669 | 0.84 | HMOX1 (0.40) | MEN1KMT2APOLBNPC1GAA | |
| SCHEMBL8442702 | 0.82 | HMOX1 (0.38) | NPC1LMNA | |
| SCHEMBL8104046 | 0.82 | HMOX1 (0.38) | POLBNPC1GAA | |
| SCHEMBL8772514 | 0.82 | HCRTR1 (0.41) | KMT2APOLBGAA | |
| SCHEMBL8443653 | 0.81 | KMT2A (0.46) | MEN1KMT2ANPC1LMNA | |
| SCHEMBL8102560 | 0.81 | HMOX1 (0.40) | POLBNPC1 | |
| SCHEMBL8772402 | 0.81 | HTR2A (0.43) | MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | claimed |