Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.78 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963208 | 0.97 | GRM5 (0.74) | GRM5MAOBGABRG2GABRB3GABRA5 | |
| SCHEMBL31060977 | 0.87 | GRM5 (1.00) | GRM5MAOBCNR1CYP11B1CYP11B2 | |
| SCHEMBL4292772 | 0.87 | GRM5 (1.00) | GRM5MAOBCNR1CYP11B1CYP11B2 | |
| SCHEMBL4297770 | 0.83 | GRM5 (1.00) | GRM5GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8546238 | 0.81 | GRM5 (0.64) | GRM5CYP11B1CYP11B2 | |
| SCHEMBL4299839 | 0.80 | GRM5 (1.00) | GRM5CYP11B1CYP11B2MRGPRX4 | |
| SCHEMBL31287796 | 0.78 | ALOX5 (0.50) | GRM5MAOBNUDT1PRMT5MEN1 | |
| SCHEMBL14744985 | 0.78 | ALOX5 (0.50) | GRM5MAOBNUDT1PRMT5MEN1 | |
| SCHEMBL24690169 | 0.77 | GRM5 (0.51) | GRM5NUDT1MEN1KMT2A | |
| SCHEMBL1901652 | 0.77 | GRM5 (0.48) | GRM5GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691277-A | REACTING A 2,6-DIHALOGENOPYRIDINE WITH A META SUBSTITUTED PHENOL | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0692474-B1 | 2- (unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy) pyridine, process for producing the same, and herbicidal composition | KUREHA CHEMICAL IND CO LTD (JP) | 1997-10-29 | — | — | EP | disclosed |
| EP-0692474-A1 | 2- (unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy) pyridine, process for producing the same, and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-01-17 | — | — | EP | disclosed |