Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540544 | 0.88 | ACHE (0.62) | ACHEALDH1A1TSHRCES2NPSR1 | |
| SCHEMBL1360237 | 0.88 | ACHE (0.62) | ACHEALDH1A1TSHRCES2NPSR1 | |
| SCHEMBL1041916 | 0.82 | RXRA (0.56) | ACHEESR1ESR2CES2POLB | |
| SCHEMBL4861345 | 0.82 | TSHR (0.47) | ACHEALDH1A1TSHRCES2NPSR1 | |
| SCHEMBL29466781 | 0.82 | RXRA (0.56) | ACHEESR1ESR2CES2POLB | |
| Ethane SCHEMBL27364386 | 0.81 | CES2 (0.67) | ALDH1A1CES2POLBNPSR1SRD5A2 | |
| SCHEMBL827199 | 0.80 | BRAF (0.46) | ACHE | |
| SCHEMBL29425720 | 0.80 | CES2 (0.71) | ALDH1A1CES2POLBNPSR1SRD5A2 | |
| SCHEMBL27989141 | 0.80 | PARP1 (0.57) | ACHEESR1ESR2TSHRCES2 | |
| SCHEMBL19310 | 0.80 | CES2 (0.71) | ALDH1A1CES2POLBNPSR1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641831-B1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD (JP) | 1997-11-12 | — | — | EP | disclosed |
| EP-0641831-A1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |