Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540544 | 1.00 | ACHE (0.62) | ACHEHDAC8RXRARXRBHDAC6 | |
| SCHEMBL8774976 | 0.88 | ACHE (0.49) | ACHEHDAC8RXRARXRBHDAC6 | |
| SCHEMBL27811835 | 0.82 | ALDH1A1 (0.44) | ACHEALDH1A1TSHRCES2KCNK9 | |
| SCHEMBL7771557 | 0.82 | ACHE (0.65) | ACHEHDAC8RXRARXRBHDAC6 | |
| SCHEMBL309330 | 0.82 | ACHE (0.65) | ACHEHDAC8RXRARXRBHDAC6 | |
| SCHEMBL2173132 | 0.82 | ACHE (0.65) | ACHEHDAC8RXRARXRBHDAC6 | |
| SCHEMBL179538 | 0.82 | RXRA (0.66) | ACHEHDAC8RXRARXRBHDAC6 | |
| SCHEMBL4861345 | 0.82 | TSHR (0.47) | ACHEALDH1A1TSHRCES2P2RX1 | |
| Ethane SCHEMBL27364386 | 0.81 | CES2 (0.67) | ALDH1A1CES2KCNK9MEN1KMT2A | |
| SCHEMBL827199 | 0.80 | BRAF (0.46) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010796-A | Small molecule inhibitor based on lactate dehydrogenase targeting design and application thereof | 南京师范大学 | 2026-05-12 | — | — | CN | disclosed |
| US-12590098-B2 | Pyrimido pyrimidinone compound and pharmaceutical composition comprising the same | AXCESO BIOPHARMA CO., LTD. (KR) | 2026-03-31 | — | — | US | disclosed |
| EP-4215533-B1 | PYRIMIDOPYRIMIDINONE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AXCESO BIOPHARMA CO LTD (KR) | 2026-02-11 | — | — | EP | disclosed |
| US-20250243161-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| US-12269800-B2 | Delivery of therapeutic alkaloid compounds | SENSORIUM THERAPEUTICS, INC. (US) | 2025-04-08 | — | — | US | disclosed |
| US-20250051277-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. | 2025-02-13 | — | — | US | disclosed |
| US-20240246910-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. | 2024-07-25 | — | — | US | disclosed |
| US-11999694-B2 | Delivery of therapeutic alkaloid compounds | SENSORIUM THERAPEUTICS, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-20230348474-A1 | PYRIMIDO PYRIMIDINONE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | AXCESO BIOPHARMA CO., LTD. (KR) | 2023-11-02 | — | — | US | disclosed |
| EP-4215533-A1 | PYRIMIDOPYRIMIDINONE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Axceso Biopharma Co., Ltd. (KR) | 2023-07-26 | — | — | EP | disclosed |
| US-20060128776-A1 | Opioid receptor active compounds | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2006-06-15 | — | — | US | disclosed |
| US-7045520-B2 | Opioid receptor active compounds | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2006-05-16 | — | — | US | disclosed |
| EP-1485088-A1 | OPIOID RECEPTOR ACTIVE 4-(3-HYDROXYPHENYL) OR 4-(3-ALKOXYPHENYL)-1,2,4-TRIAZOLE COMPOUNDS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20030225072-A1 | Opioid receptor active compounds | CURATORS OF THE UNIVERSITY OF MISSOURI, THE | 2003-12-04 | — | — | US | disclosed |
| WO-2003066050-A1 | OPIOID RECEPTOR ACTIVE 4-(3-HYDROXYPHENYL) OR 4-(3-ALKOXYPHENYL)-1,2,4-TRIAZOLE COMPOUNDS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2003-08-14 | — | — | WO | disclosed |
| EP-0659738-B1 | N-(Carbonyl, carbonimidoyl, carbonothioyl) sulfonamide charge control agents and toners and developers | EASTMAN KODAK CO (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5616797-A | USED IN ELECTROPHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1997-04-01 | — | — | US | disclosed |
| EP-0659738-A1 | N-(Carbonyl, carbonimidoyl, carbonothioyl) sulfonamide charge control agents and toners and developers | EASTMAN KODAK COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
| US-5405727-A | Electrophotography | EASTMAN KODAK COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225072-A1 | Opioid receptor active compounds | OPRL1, OPRM1, OPRK1 | ACHE 876/4885HDAC8 2536/4885RXRA 406/4885 |
| US-20250051277-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | PNMT, HNMT, NNMT | ACHE 37/4885HDAC8 2225/4885RXRA 4547/4885 |
| US-20250243161-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | PNMT, HNMT, NNMT | ACHE 37/4885HDAC8 2225/4885RXRA 4547/4885 |
| US-20240246910-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | PNMT, HNMT, NNMT | ACHE 37/4885HDAC8 2225/4885RXRA 4547/4885 |
| US-20230348474-A1 | PYRIMIDO PYRIMIDINONE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | PDCD1, PDCD1LG2, CD274 | ACHE 4640/4885HDAC8 1211/4885RXRA 1329/4885 |
| US-20060128776-A1 | Opioid receptor active compounds | OPRL1, OPRM1, OPRK1 | ACHE 513/4885HDAC8 2607/4885RXRA 338/4885 |
| US-12269800-B2 | Delivery of therapeutic alkaloid compounds | PNMT, HNMT, NNMT | ACHE 37/4885HDAC8 2225/4885RXRA 4547/4885 |
| US-11999694-B2 | Delivery of therapeutic alkaloid compounds | PNMT, HNMT, NNMT | ACHE 37/4885HDAC8 2225/4885RXRA 4547/4885 |
| US-12590098-B2 | Pyrimido pyrimidinone compound and pharmaceutical composition comprising the same | PDCD1, CD274, PDCD1LG2 | ACHE 4810/4885HDAC8 419/4885RXRA 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.