Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775028 | 1.00 | OPRM1 (0.32) | OPRM1OPRL1POLBPIK3CAMTOR | |
| SCHEMBL8623005 | 0.82 | — | — | |
| SCHEMBL8623002 | 0.82 | — | — | |
| SCHEMBL7358020 | 0.66 | VNN1 (0.35) | OPRM1OPRL1 | |
| SCHEMBL7358018 | 0.66 | VNN1 (0.35) | OPRM1OPRL1 | |
| SCHEMBL10661170 | 0.60 | POLB (0.52) | POLB | |
| SCHEMBL7358026 | 0.59 | P2RX7 (0.41) | PIK3CAMTOR | |
| SCHEMBL8439682 | 0.58 | VNN1 (0.36) | OPRM1OPRL1 | |
| SCHEMBL20489483 | 0.58 | MAP4K4 (0.45) | OPRM1POLB | |
| SCHEMBL9818613 | 0.56 | OPRM1 (0.40) | OPRM1OPRL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655057-B1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS | UPJOHN CO (US) | 1997-09-17 | — | — | EP | claimed |