SCHEMBL8775411

SCHEMBL8775411

O=C(Cl)c1ccc(C(=O)Cl)c(-c2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC7 Q8WUI4 1/20 0.42
L3MBTL3 Q96JM7 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
BCAT2 O15382 1/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
PTPN1 P18031 1/20 0.40
BACE1 P56817 1/20 0.39
ALOX15 P16050 1/20 0.38
CDC25B P30305 2/20 0.38
HNF4A P41235 2/20 0.38
CDC25A P30304 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ATM Q13315 1/20 0.38
TTR P02766 1/20 0.38
ACMSD Q8TDX5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11750400 0.91 PTPN1 (0.46) HDAC7L3MBTL3L3MBTL1ALDH1A1PTPN1
Benzene SCHEMBL28149666 0.91 PTPN1 (0.46) HDAC7L3MBTL3L3MBTL1ALDH1A1PTPN1
SCHEMBL9490431 0.85 BCAT2 (0.44) BCAT2ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL28493463 0.85 ADORA3 (0.40) L3MBTL1ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL10917657 0.82 BCAT2 (0.47) HDAC7BCAT2ALDH1A1SMN1; SMN2MEN1
SCHEMBL1353027 0.81 PTGS2 (0.49) L3MBTL1ALDH1A1MAPTSMN1; SMN2PTPN1
SCHEMBL9532086 0.80 BCAT2 (0.55) BCAT2ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL28040744 0.80 ALDH1A1 (0.41) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9860754 0.79 BCAT2 (0.44) HDAC7BCAT2ALDH1A1SMN1; SMN2MEN1
SCHEMBL229441 0.78 BCAT2 (0.63) BCAT2ALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109768320-B All-solid-state polymer electrolyte, preparation method thereof and all-solid-state lithium ion battery 南方科技大学 2021-05-07 CN claimed
CN-116802774-A Hollow microsphere 株式会社德山 2023-09-22 CN disclosed
CN-115916463-A Microspheres containing polymerizable functional groups 株式会社德山 2023-04-04 CN disclosed
CN-115428128-A Hollow microspheres 株式会社德山 2022-12-02 CN disclosed
CN-115379926-A Hollow microspheres for CMP polishing pads 株式会社德山 2022-11-22 CN disclosed
CN-109768320-B All-solid-state polymer electrolyte, preparation method thereof and all-solid-state lithium ion battery 南方科技大学 2021-05-07 CN disclosed
EP-0641831-B1 Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same DOW CORNING ASIA LTD (JP) 1997-11-12 EP disclosed
US-5464922-A Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same DOW CORNING ASIA LTD. (JP) 1995-11-07 US disclosed
EP-0641831-A1 Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same DOW CORNING ASIA, Ltd. (JP) 1995-03-08 EP disclosed
US-5078907-A UNSYMMETRICAL DICARBOXYLIC ESTERS AS BLEACH PRECURSORS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-01-07 US disclosed
EP-0426217-A2 Bleach precursors UNILEVER N.V. (NL) 1991-05-08 EP disclosed