Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.63 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775912 | 0.79 | CA12 (0.41) | ALOX5TRPM8HTT | |
| SCHEMBL8775901 | 0.79 | ALDH1A1 (0.47) | HTTALDH1A1 | |
| SCHEMBL8776036 | 0.78 | ALOX5 (0.52) | ALOX5TRPM8HTTKCNA5 | |
| SCHEMBL8775896 | 0.77 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL8775797 | 0.74 | MMP1 (0.45) | ALOX5HTTKCNA5ALDH1A1 | |
| SCHEMBL8775835 | 0.72 | MAOA (0.43) | HTTKCNA5ALDH1A1 | |
| SCHEMBL8775947 | 0.72 | MAPK1 (0.47) | HTT | |
| SCHEMBL13524545 | 0.72 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL27687109 | 0.70 | SMN1; SMN2 (0.50) | HTTKCNA5ALDH1A1 | |
| SCHEMBL9476354 | 0.69 | ALOX5 (0.64) | ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |