Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775901 | 0.88 | ALDH1A1 (0.47) | ALDH1A1GPR132KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6201975 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP19A1CYP11B1CYP11B2KDM4E | |
| SCHEMBL8775894 | 0.77 | SLC7A5 (0.55) | ALDH1A1GPR132KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL8775748 | 0.77 | ALOX5 (0.63) | ALDH1A1 | |
| SCHEMBL27417521 | 0.76 | MEN1 (0.49) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8775835 | 0.76 | MAOA (0.43) | ALDH1A1CYP11B1CYP11B2KDM4EMAPT | |
| SCHEMBL10692307 | 0.76 | CYP19A1 (0.60) | ALDH1A1CYP19A1CYP11B1CYP11B2KDM4E | |
| SCHEMBL8775947 | 0.76 | MAPK1 (0.47) | GPR132MAPTSMN1; SMN2 | |
| SCHEMBL14408276 | 0.75 | PPARA (0.64) | ALDH1A1KDM4ESMN1; SMN2TSHRNPC1 | |
| SCHEMBL27530951 | 0.75 | ALDH1A1 (0.70) | ALDH1A1CYP19A1CYP11B1CYP11B2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |