Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779192 | 0.91 | KDM4E (0.39) | LTA4HMMP2KDM4EALDH1A1LMNA | |
| SCHEMBL8779198 | 0.86 | LTA4H (0.46) | LTA4HXIAPACACBKDM4EALDH1A1 | |
| SCHEMBL8779260 | 0.85 | MME (0.39) | ADAM17PTGER1ALDH1A1L3MBTL1 | |
| SCHEMBL8779153 | 0.84 | CARM1 (0.40) | CARM1PRMT6LTA4HACACBKDM4E | |
| SCHEMBL8779302 | 0.84 | PLAU (0.36) | LTA4HANO1PLAUPTGER1ALDH1A1 | |
| SCHEMBL8881529 | 0.83 | CARM1 (0.39) | CARM1PRMT6LTA4HXIAPBIRC2 | |
| SCHEMBL8779316 | 0.83 | MME (0.39) | — | |
| SCHEMBL8779212 | 0.82 | HPGD (0.38) | CARM1PRMT6AAK1KDM4EALDH1A1 | |
| SCHEMBL8779176 | 0.82 | HPGD (0.38) | CARM1PRMT6AAK1KDM4EALDH1A1 | |
| SCHEMBL8779292 | 0.82 | CARM1 (0.35) | CARM1PRMT6AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |