Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779316 | 0.90 | MME (0.39) | KDM5AMMEACECPA1ACE2 | |
| SCHEMBL8779192 | 0.90 | KDM4E (0.39) | KMT2AALDH1A1RAB9AMEN1LMNA | |
| SCHEMBL8779198 | 0.89 | LTA4H (0.46) | ALDH1A1RAB9AMAPTL3MBTL1KDM4E | |
| SCHEMBL8779265 | 0.87 | TRPV1 (0.38) | ACACBLTA4H | |
| SCHEMBL8779134 | 0.84 | CARM1 (0.38) | CARM1PRMT6ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8779260 | 0.84 | MME (0.39) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL8779285 | 0.84 | KDM4E (0.40) | CARM1KMT2AALDH1A1CNR1CNR2 | |
| SCHEMBL8779212 | 0.83 | HPGD (0.38) | CARM1PRMT6KMT2AALDH1A1LMNA | |
| SCHEMBL8779176 | 0.83 | HPGD (0.38) | CARM1PRMT6KMT2AALDH1A1LMNA | |
| SCHEMBL8882530 | 0.83 | KMT2A (0.41) | CARM1PRMT6KMT2AALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |