Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779246 | 0.89 | MAOB (0.43) | ALDH1A1MAOB | |
| SCHEMBL8779168 | 0.89 | SMN1; SMN2 (0.40) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL8779406 | 0.89 | LTA4H (0.44) | RAB9AMAPTL3MBTL1PARP10SMN1; SMN2 | |
| SCHEMBL8779331 | 0.86 | MMP1 (0.41) | KMT2AMEN1MAOBSMN1; SMN2 | |
| SCHEMBL8786130 | 0.86 | KMT2A (0.45) | KDM4EEPHX2ALDH1A1KMT2ARAB9A | |
| SCHEMBL8785043 | 0.86 | NPBWR1 (0.41) | KDM4EEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8779153 | 0.84 | CARM1 (0.40) | KDM4EALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL8779302 | 0.83 | PLAU (0.36) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL8779187 | 0.83 | MRGPRX4 (0.37) | ALDH1A1L3MBTL1MAOB | |
| SCHEMBL8883279 | 0.82 | KMT2A (0.44) | KDM4EEPHX2ALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |