Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779263 | 1.00 | OPRK1 (0.37) | OPRK1MEN1NR1I2LMNACHRM2 | |
| SCHEMBL8779180 | 0.97 | PTGES (0.38) | OPRK1CTSKCTSLCTSBCTSH | |
| SCHEMBL8779075 | 0.94 | OPRK1 (0.41) | OPRK1CYP3A4MAPTCITCTSC | |
| SCHEMBL8779351 | 0.90 | OPRK1 (0.40) | OPRK1CITCTSCOPRM1OPRD1 | |
| SCHEMBL8779204 | 0.86 | KDM4E (0.39) | OPRK1CYP3A4CITLTA4HCTSC | |
| SCHEMBL8779164 | 0.86 | KDM4E (0.39) | OPRK1CYP3A4CITLTA4HCTSC | |
| SCHEMBL8779165 | 0.86 | XIAP (0.38) | OPRK1MEN1NR1I2LMNACHRM2 | |
| SCHEMBL8882433 | 0.85 | PTPN1 (0.42) | OPRK1MEN1NR1I2LMNACHRM2 | |
| SCHEMBL8779188 | 0.85 | CTSC (0.37) | OPRK1CYP3A4CITCTSCOPRM1 | |
| SCHEMBL8779157 | 0.82 | XIAP (0.40) | LMNACYP3A4S1PR1S1PR3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |