Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 7/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779191 | 0.88 | IRAK4 (0.38) | IRAK4CCNA2CDK2CCNA1ACACB | |
| SCHEMBL8779229 | 0.87 | IRAK4 (0.40) | IRAK4CNR1CNR2CCNA2CDK2 | |
| SCHEMBL8779428 | 0.87 | IRAK4 (0.43) | IRAK4ACACBLMNA | |
| SCHEMBL8882156 | 0.85 | IRAK4 (0.38) | IRAK4CNR1CNR2PPARGCTSK | |
| SCHEMBL8779225 | 0.80 | PARP15 (0.40) | IRAK4CNR1CNR2CCNA2CDK2 | |
| SCHEMBL8779239 | 0.78 | LNPEP (0.40) | PPARGLNPEP | |
| SCHEMBL8779243 | 0.77 | PPARG (0.38) | IRAK4PPARGLNPEPACACBLMNA | |
| SCHEMBL8779418 | 0.76 | PPARG (0.36) | IRAK4PPARGLNPEPACACBLMNA | |
| SCHEMBL8779157 | 0.75 | XIAP (0.40) | SLC15A1ACACBLMNA | |
| SCHEMBL8779135 | 0.75 | XIAP (0.40) | SLC15A1ACACBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |