Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 13/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779229 | 0.91 | IRAK4 (0.40) | LNPEPAAK1 | |
| SCHEMBL8779243 | 0.91 | PPARG (0.38) | LNPEPPPARGKITPDGFRA | |
| SCHEMBL8779418 | 0.89 | PPARG (0.36) | LNPEPPPARGKITPDGFRA | |
| SCHEMBL8779100 | 0.86 | LNPEP (0.42) | LNPEPAAK1 | |
| SCHEMBL8882315 | 0.85 | LNPEP (0.41) | LNPEPAAK1PPARG | |
| SCHEMBL8779223 | 0.85 | AAK1 (0.39) | AAK1 | |
| SCHEMBL8779220 | 0.83 | AAK1 (0.40) | LNPEPAAK1 | |
| SCHEMBL8779390 | 0.82 | NFE2L2 (0.38) | LNPEPPPARGKITPDGFRA | |
| SCHEMBL8779334 | 0.81 | LNPEP (0.42) | LNPEPAAK1 | |
| SCHEMBL8779428 | 0.81 | IRAK4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |