Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779260 | 0.92 | MME (0.39) | L3MBTL1ALDH1A1GAAMRGPRX4PTPN1 | |
| SCHEMBL8779316 | 0.90 | MME (0.39) | MAOBPTPN1NR3C2PPIA | |
| SCHEMBL8779269 | 0.86 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1GAAMAPTHTT | |
| SCHEMBL8779198 | 0.85 | LTA4H (0.46) | L3MBTL1ALDH1A1MAPT | |
| SCHEMBL8882204 | 0.85 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1GAAMAPTHTT | |
| SCHEMBL8779232 | 0.82 | GSK3B (0.39) | ALDH1A1MAPT | |
| SCHEMBL8779153 | 0.82 | CARM1 (0.40) | L3MBTL1ALDH1A1MAPTSLC1A5 | |
| SCHEMBL8779265 | 0.81 | TRPV1 (0.38) | MRGPRX4 | |
| SCHEMBL8779134 | 0.81 | CARM1 (0.38) | L3MBTL1ALDH1A1HTT | |
| SCHEMBL8779192 | 0.80 | KDM4E (0.39) | L3MBTL1ALDH1A1MRGPRX4MAOBSLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |