Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779178 | 0.88 | PRKD3 (0.33) | GPR88 | |
| SCHEMBL8779424 | 0.87 | MAPK8 (0.37) | — | |
| SCHEMBL8779132 | 0.85 | ACACB (0.34) | — | |
| SCHEMBL8779023 | 0.84 | KDM4E (0.36) | — | |
| SCHEMBL8779161 | 0.83 | SMPD1 (0.39) | — | |
| SCHEMBL8779185 | 0.82 | ACACB (0.37) | — | |
| SCHEMBL8883190 | 0.81 | THRA (0.32) | — | |
| SCHEMBL8779219 | 0.81 | ACACB (0.34) | — | |
| SCHEMBL8779296 | 0.81 | MEN1 (0.33) | — | |
| SCHEMBL8779309 | 0.79 | L3MBTL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |