Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.34 |
| ▸ | ACACA | Q13085 | 3/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779178 | 0.85 | PRKD3 (0.33) | ACACBALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL8779424 | 0.84 | MAPK8 (0.37) | ACACBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8779185 | 0.83 | ACACB (0.37) | ACACBALDH1A1HPGDHSD17B10 | |
| SCHEMBL8779132 | 0.81 | ACACB (0.34) | ACACBACACAALDH1A1ADORA2AHSD17B10 | |
| SCHEMBL8779357 | 0.81 | GPR88 (0.32) | — | |
| SCHEMBL8779023 | 0.81 | KDM4E (0.36) | KDM4E | |
| SCHEMBL8779296 | 0.80 | MEN1 (0.33) | ACACBALDH1A1HPGD | |
| SCHEMBL8882475 | 0.80 | SYK (0.36) | ACACBACACASYKADORA2A | |
| SCHEMBL8779309 | 0.78 | L3MBTL1 (0.39) | ALDH1A1 | |
| SCHEMBL8779211 | 0.77 | MEN1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |