Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 3/20 | 0.57 |
| ▸ | SRC | P12931 | 3/20 | 0.57 |
| ▸ | ABCC8 | Q09428 | 4/20 | 0.57 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3612969 | 0.84 | SMN1; SMN2 (0.76) | MEN1KMT2ASMN1; SMN2KDM4EGAA | |
| SCHEMBL8779355 | 0.79 | RAB9A (0.70) | MEN1KMT2ASMN1; SMN2KDM4EGAA | |
| SCHEMBL11440911 | 0.79 | CA1 (0.66) | MEN1KMT2ASMN1; SMN2KDM4EGAA | |
| SCHEMBL8779366 | 0.77 | ABL1 (0.84) | MEN1KMT2ASMN1; SMN2KDM4EGAA | |
| SCHEMBL9403495 | 0.76 | SMN1; SMN2 (0.56) | MEN1KMT2ASMN1; SMN2KDM4EGAA | |
| SCHEMBL28451175 | 0.76 | ABL1 (0.67) | MEN1KMT2ASMN1; SMN2KDM4EGAA | |
| SCHEMBL8779318 | 0.75 | ABL1 (0.65) | MEN1KMT2ASMN1; SMN2KDM4EGAA | |
| SCHEMBL3263155 | 0.74 | LMNA (0.72) | MEN1KMT2ASMN1; SMN2KDM4EGAA | |
| SCHEMBL7483795 | 0.73 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2KDM4EGAA | |
| SCHEMBL8779324 | 0.73 | ALDH1A1 (0.59) | MEN1KMT2ASMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | disclosed |
| US-5401853-A | Thiadiazole derivatives for the treatment of depressive states | LABORATORIO FARMACEUTICO C.T. S.R.L. (IT) | 1995-03-28 | — | — | US | disclosed |