Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.38 |
| ▸ | S100A10 | P60903 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779845 | 0.91 | MMP13 (0.51) | MMP13MMP8MMP3ANXA2S100A10 | |
| SCHEMBL8779885 | 0.83 | CA2 (0.41) | MMP13MMP8CYP3A4TSHRMAPK1 | |
| SCHEMBL2739640 | 0.75 | ALDH1A1 (0.40) | STSMMP13MMP8MMP3ANXA2 | |
| SCHEMBL8677277 | 0.75 | DNMT1 (0.35) | TSHRDNMT1CA2CA12CA1 | |
| SCHEMBL19975469 | 0.75 | CA2 (0.52) | KDM4ECA2CA12CA1LMNA | |
| SCHEMBL8779793 | 0.74 | ALDH1A1 (0.52) | STSMMP13MMP8MMP3ANXA2 | |
| Potassium Ion SCHEMBL978255 | 0.74 | STS (0.41) | STSMMP13MMP8MMP3ANXA2 | |
| SCHEMBL979380 | 0.74 | LMNA (0.56) | STSMMP13MMP8MMP3ANXA2 | |
| SCHEMBL1415839 | 0.74 | LMNA (0.43) | STSMMP13MMP8MMP3ANXA2 | |
| SCHEMBL10396837 | 0.73 | CA2 (0.48) | MMP13MMP8ANXA2S100A10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770599-A1 | PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |