Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.38 |
| ▸ | S100A10 | P60903 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415839 | 0.95 | LMNA (0.43) | STSMMP13MMP8MMP3ANXA2 | |
| Potassium Ion SCHEMBL11617203 | 0.91 | MMP13 (0.51) | MMP13MMP8MMP3ANXA2S100A10 | |
| Potassium Ion SCHEMBL11610857 | 0.89 | ALDH1A1 (0.48) | MMP13MMP8LMNACYP3A4MAPK1 | |
| SCHEMBL11337395 | 0.86 | MMP13 (0.51) | MMP13MMP8MMP3ANXA2S100A10 | |
| Potassium Ion SCHEMBL1538011 | 0.83 | LMNA (0.48) | LMNATDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL565077 | 0.79 | LMNA (0.43) | LMNATDP1DNMT1HPGDL3MBTL1 | |
| SCHEMBL11319549 | 0.77 | LMNA (0.34) | MMP13MMP8MMP3LMNATDP1 | |
| SCHEMBL19953365 | 0.76 | LMNA (0.55) | LMNATDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL28934944 | 0.76 | LMNA (0.48) | LMNATDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL28993337 | 0.75 | TSHR (0.50) | LMNATDP1TSHRMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150594-A1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING SAME | 帝人株式会社 | 2024-07-18 | — | — | WO | disclosed |
| US-12024629-B2 | Polycarbonate-based resin, production method therefor, and polycarbonate-based resin composition | IDEMITSU KOSAN CO., LTD. (JP) | 2024-07-02 | — | — | US | disclosed |
| US-20240199849-A1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES | IDEMITSU KOSAN CO.,LTD. (JP) | 2024-06-20 | — | — | US | disclosed |
| EP-3623427-B1 | RESIN COMPOSITION AND MOLDED ARTICLE | DAIKIN IND LTD (JP) | 2024-05-22 | — | — | EP | disclosed |
| US-20240150574-A1 | POLYCARBONATE RESIN COMPOSITION | IDEMITSU KOSAN CO.,LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| WO-2024053274-A1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE FORMED OF SAME | 帝人株式会社 | 2024-03-14 | — | — | WO | disclosed |
| EP-4321555-A1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES | Idemitsu Kosan Co.,Ltd. (JP) | 2024-02-14 | — | — | EP | disclosed |
| CN-117440989-A | Polycarbonate resin composition and molded article | 出光兴产株式会社 | 2024-01-23 | — | — | CN | disclosed |
| CN-117120548-A | Polycarbonate resin composition and molded article | 出光兴产株式会社 | 2023-11-24 | — | — | CN | disclosed |
| WO-2023176396-A1 | AROMATIC POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | 帝人株式会社 | 2023-09-21 | — | — | WO | disclosed |
| US-7160937-B2 | Flame retardant aromatic polycarbonate resin composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1338625-B1 | FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION | KANEKA CORP (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-20050256227-A1 | Flame-retardant aromatic polycarbonate resin composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1288262-B1 | Flame retardant aromatic polycarbonate resin composition and molded articles thereof | TEIJIN CHEMICALS LTD (JP) | 2005-10-12 | — | — | EP | disclosed |
| US-20050154103-A1 | Blend with organic acid, sulfonic acid ester, or monomeric acid anhydride; alkali or alkaline earth metal salt carboxylate; and fluoropolymer; melt stability; heat, impact and aging resistance; waterproofing; injection and extrusion molding | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2005-07-14 | — | — | US | disclosed |
| US-6727303-B2 | STYRENE-BASED RESIN, AROMATIC POLYESTER RESIN AND SILICONE; TRANSPARENCY | TEIJIN CHEMICALS, LTD. (JP) | 2004-04-27 | — | — | US | disclosed |
| EP-1338625-A1 | FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION | KANEKA CORPORATION (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-20030158309-A1 | Flame retardant aromatic polycarbonate resin composition and molded articles thereof | TEIJIN CHEMICALS LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1288262-A2 | Flame retardant aromatic polycarbonate resin composition and molded articles thereof | Teijin Chemicals, Ltd. (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-4113695-A | Non-opaque flame-retardant polycarbonate composition | GENERAL ELECTRIC COMPANY (US) | 1978-09-12 | — | — | US | disclosed |