SCHEMBL19975469

SCHEMBL19975469

O=S(=O)(Br)c1ccc(-c2ccc(S(=O)(=O)Br)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 11/20 0.52
CA12 O43570 10/20 0.52
CA9 Q16790 10/20 0.52
CA1 P00915 7/20 0.44
CA14 Q9ULX7 5/20 0.44
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HTT P42858 1/20 0.41
PKM P14618 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
KIF11 P52732 1/20 0.38
MMP2 P08253 1/20 0.37
MMP7 P09237 1/20 0.37
MMP14 P50281 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779885 0.90 CA2 (0.41) CA2CA12CA9CA1CA14
SCHEMBL7605554 0.79 CA2 (0.59) CA2CA12CA9CA1CA14
SCHEMBL4315677 0.77 ALDH1A1 (0.62) CA2CA12CA9CA1CA14
SCHEMBL31086968 0.77 TSHR (0.62) CA2CA12CA9CA1CA14
SCHEMBL9573621 0.77 MMP2 (0.50) CA2CA1PKMALDH1A1MMP2
SCHEMBL1153998 0.77 GAA (0.62) CA2CA12CA9CA1SMN1; SMN2
SCHEMBL296383 0.75 HTR6 (0.58) CA2CA12CA9CA1CA14
SCHEMBL8779813 0.75 STS (0.41) CA2CA12CA1LMNAKDM4E
SCHEMBL21114887 0.75 HTR2A (0.39) CA2CA12CA9CA1CA14
SCHEMBL8996770 0.73 TSHR (0.42) CA2CA12CA9CA1CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10869884-B2 Cyclodextrin based polymers, methods, compositions and applications thereof ATEN PORUS LIFESCIENCES (IN) 2020-12-22 US disclosed
EP-3515501-A1 CYCLODEXTRIN BASED POLYMERS, METHODS, COMPOSITIONS AND APPLICATIONS THEREOF Aten Porus Lifesciences (IN) 2019-07-31 EP disclosed
US-20190209605-A1 CYCLODEXTRIN BASED POLYMERS, METHODS, COMPOSITIONS AND APPLICATIONS THEREOF ATEN PORUS LIFESCIENCES (IN) 2019-07-11 US disclosed
WO-2018051298-A1 CYCLODEXTRIN BASED POLYMERS, METHODS, COMPOSITIONS AND APPLICATIONS THEREOF ATEN PORUS LIFESCIENCES (IN) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10869884-B2 Cyclodextrin based polymers, methods, compositions and applications thereof NPC1L1, CETP, LIPA CA2 1967/4885CA12 1288/4885CA9 874/4885
US-20190209605-A1 CYCLODEXTRIN BASED POLYMERS, METHODS, COMPOSITIONS AND APPLICATIONS THEREOF NPC1L1, CETP, LIPA CA2 1967/4885CA12 1288/4885CA9 874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.