Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.51 |
| ▸ | SCD | O00767 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779899 | 1.00 | LMNA (0.59) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8779898 | 1.00 | LMNA (0.59) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL11989038 | 0.80 | ALDH1A1 (0.61) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL11499385 | 0.79 | RAB9A (0.54) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL7301655 | 0.78 | CYP3A4 (0.58) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5366964 | 0.78 | LMNA (0.51) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5133337 | 0.78 | LMNA (0.53) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1106998 | 0.77 | LMNA (0.69) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL17137526 | 0.77 | FAAH (0.53) | LMNANPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL20028055 | 0.77 | LMNA (0.56) | LMNANPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651552-A | Therapeutic or prophylactic agent for covd-19 | 国立大学法人广岛大学 | 2024-03-05 | — | — | CN | disclosed |
| CN-111201215-B | Novel amide compound, pin1 inhibitor using same, therapeutic agent for inflammatory disease, and therapeutic agent for cancer | 国立大学法人广岛大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-115397466-A | Novel 3,5-diaminobenzoic acid-based compound, pin1 inhibitor using same, and therapeutic agent for inflammatory disease | 国立大学法人广岛大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-111201215-A | Novel amide compound, Pin1 inhibitor using same, therapeutic agent for inflammatory disease, and therapeutic agent for cancer | 国立大学法人广岛大学 | 2020-05-26 | — | — | CN | disclosed |
| CN-111182896-A | Therapeutic agent for fatty liver disease and therapeutic agent for obesity | 国立大学法人广岛大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-111183129-A | Novel anthranilic acid compound, Pin1 inhibitor using same, and therapeutic agent for inflammatory disease and cancer | 国立大学法人广岛大学 | 2020-05-19 | — | — | CN | disclosed |
| EP-0539057-B1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PROD (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0198271-B1 | PEPTIDES | MERCK PATENT GmbH (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0539057-A1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5124319-A | Administering for treatment of neuropathological disorders induced by overstimulation of excitatory amino acid receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0272444-A2 | Renin-inhibiting peptides | MERCK PATENT GmbH (DE) | 1988-06-29 | — | — | EP | disclosed |
| EP-0262318-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-04-06 | — | — | EP | disclosed |
| US-4721776-A | Amino acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-01-26 | — | — | US | disclosed |
| EP-0222283-A2 | Amino-acid derivatives | MERCK PATENT GmbH (DE) | 1987-05-20 | — | — | EP | disclosed |
| EP-0220665-A2 | Peptides | MERCK PATENT GmbH (DE) | 1987-05-06 | — | — | EP | disclosed |
| US-4170654-A | Antihypertensive compositions containing N-heterocyclicalanines and α- | MERCK & CO., INC. (US) | 1979-10-09 | — | — | US | disclosed |
| US-4160835-A | Antihypertensive compositions containing an arylsubstituted alanine and a phenyl hydrazinopropionic acid | MERCK & CO., INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4156734-A | Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid | MERCK & CO., INC. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4149011-A | Novel substituted alanines | MERCK & CO., INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-4070478-A | Benzimidazole substituted alanines | MERCK & CO., INC. (US) | 1978-01-24 | — | — | US | disclosed |