Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CHRNE | Q04844 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780933 | 0.97 | SLC6A4 (0.42) | SLC6A4SLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL8780893 | 0.87 | KCNH2 (0.59) | SLC6A4SLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL8780946 | 0.85 | ADORA2A (0.43) | KCNH2KMT2AMAOAMAOBACHE | |
| SCHEMBL8780869 | 0.80 | KCNH2 (0.42) | SLC6A4SLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL8780779 | 0.80 | KCNH2 (0.51) | SLC6A4SLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL8780892 | 0.79 | RXFP1 (0.42) | KCNH2KMT2A | |
| SCHEMBL8780858 | 0.78 | ALDH1A1 (0.44) | SLC6A4SLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL8780905 | 0.78 | GPR84 (0.40) | SLC6A4SLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL8780827 | 0.78 | SLC6A4 (0.44) | SLC6A4SLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL8780974 | 0.78 | DRD2 (0.42) | DRD1ADRA1AOPRM1DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |