Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780892 | 0.88 | RXFP1 (0.42) | ADORA2AADORA1KCNH2MCHR1MAPT | |
| SCHEMBL8780868 | 0.87 | MAOB (0.41) | ADORA2AADORA1KDM4EMAOBMAOA | |
| SCHEMBL8780878 | 0.85 | SLC6A4 (0.43) | MAOBMAOAACHEKCNH2KMT2A | |
| SCHEMBL8780783 | 0.83 | HTR1D (0.41) | KDM4EKCNH2MCHR1KMT2A | |
| SCHEMBL8780909 | 0.82 | KCNH2 (0.42) | ADORA2AADORA1KCNH2MCHR1MAPT | |
| SCHEMBL8780789 | 0.82 | ADORA2A (0.41) | ADORA2AADORA1KDM4ETSHRKCNH2 | |
| SCHEMBL8780933 | 0.82 | SLC6A4 (0.42) | MAOBMAOAACHEKCNH2KMT2A | |
| SCHEMBL8780829 | 0.82 | RIPK2 (0.43) | ADORA2AADORA1KDM4ETSHRMAOB | |
| SCHEMBL8780998 | 0.81 | SLC6A4 (0.42) | ADORA2AADORA1KCNH2MCHR1MAPT | |
| SCHEMBL8780841 | 0.81 | ALDH1A1 (0.43) | KDM4EMAOBMCHR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |