Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780886 | 0.76 | CYP1A2 (0.47) | MAPTPOLBTSHRNPSR1HSD17B10 | |
| SCHEMBL8780809 | 0.74 | GPR84 (0.46) | MAPTNPSR1HSD17B10PLA2G7CYP1A2 | |
| SCHEMBL8780985 | 0.71 | GPR84 (0.42) | POLBTSHRNPSR1HSD17B10L3MBTL1 | |
| SCHEMBL8780883 | 0.71 | GPR84 (0.42) | POLBTSHRNPSR1HSD17B10L3MBTL1 | |
| SCHEMBL8780970 | 0.71 | GPR84 (0.42) | POLBTSHRNPSR1HSD17B10L3MBTL1 | |
| SCHEMBL8780944 | 0.69 | TAAR1 (0.60) | TSHRMAPK1TAAR1ALDH1A1 | |
| SCHEMBL8780755 | 0.68 | MAPK1 (0.47) | MAPTPOLBTSHRNPSR1HSD17B10 | |
| SCHEMBL8780906 | 0.68 | DRD2 (0.56) | POLBTSHRPLA2G7RXFP1KMT2A | |
| SCHEMBL8780808 | 0.68 | TAAR1 (0.45) | CYP1A2MAPK1TAAR1RXFP1ALDH1A1 | |
| SCHEMBL12291287 | 0.67 | RXFP1 (0.43) | MAPTPOLBTSHRNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |