SCHEMBL8782864

SCHEMBL8782864

Cc1ccccc1N(C)C(=O)n1ccc(S(=O)(=O)c2cc(Cl)cc(Cl)c2)n1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 5/20 0.35
HSD17B2 P37059 5/20 0.35
GPBAR1 Q8TDU6 4/20 0.35
ACLY P53396 2/20 0.34
STS P08842 4/20 0.34
CNR1 P21554 1/20 0.34
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8783890 0.90 CNR1 (0.36) GPBAR1ACLYCNR1MEN1KMT2A
SCHEMBL8783288 0.82 SCN4A (0.36) ACLYCNR1ALDH1A1MEN1KMT2A
SCHEMBL8782632 0.82 ALDH1A1 (0.38) GPBAR1ALDH1A1MEN1KMT2A
SCHEMBL8783286 0.82 GPBAR1 (0.36) HSD17B1HSD17B2GPBAR1ACLYSTS
SCHEMBL9260183 0.82 LMNA (0.41) HSD17B1HSD17B2GPBAR1ALDH1A1MEN1
SCHEMBL8782648 0.81 HTR3E (0.39) HSD17B1HSD17B2GPBAR1MEN1KMT2A
SCHEMBL8782580 0.78 HTR6 (0.34) CNR1ALDH1A1
SCHEMBL8782179 0.78 SIRT2 (0.33) GPBAR1CNR1ALDH1A1MEN1KMT2A
SCHEMBL8782628 0.77 ALDH1A1 (0.35) CNR1ALDH1A1KMT2A
SCHEMBL8782563 0.75 AHR (0.38) CNR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493925-B1 Pyrazole derivatives having herbicidal activity, their preparation and their use SANKYO CO (JP) 1997-11-05 EP disclosed
US-5424279-A Useful for rice crops SANKYO COMPANY, LIMITED (JP) 1995-06-13 US disclosed
EP-0493925-A1 Pyrazole derivatives having herbicidal activity, their preparation and their use Sankyo Company Limited (JP) 1992-07-08 EP disclosed