SCHEMBL8783288

SCHEMBL8783288

CN(C)C(=O)n1ccc(S(=O)(=O)c2cc(Cl)cc(Cl)c2)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 1/20 0.36
HTR6 P50406 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CNR1 P21554 4/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.32
LIPE Q05469 1/20 0.32
KDM1A O60341 1/20 0.32
NAMPT P43490 2/20 0.32
ACLY P53396 1/20 0.32
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8782580 0.87 HTR6 (0.34) HTR6ALDH1A1CNR1TSHRKDM1A
SCHEMBL8782632 0.86 ALDH1A1 (0.38) ALDH1A1KMT2AMEN1ACHELIPE
SCHEMBL8782628 0.86 ALDH1A1 (0.35) HTR6ALDH1A1CNR1KMT2ATSHR
SCHEMBL8782563 0.84 AHR (0.38) HTR6CNR1KMT2AMEN1LMNA
SCHEMBL8783890 0.83 CNR1 (0.36) HTR6CNR1KMT2AMEN1KDM1A
SCHEMBL8782648 0.83 HTR3E (0.39) KMT2AMEN1PDE4BLMNAMAPT
SCHEMBL8782387 0.83 MEN1 (0.37) HTR6ALDH1A1KMT2AMEN1TSHR
SCHEMBL8782433 0.83 GPBAR1 (0.35) ALDH1A1CNR1KMT2AMEN1LIPE
SCHEMBL8782864 0.82 HSD17B1 (0.35) ALDH1A1CNR1KMT2AMEN1ACLY
SCHEMBL8782179 0.82 SIRT2 (0.33) HTR6ALDH1A1CNR1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493925-B1 Pyrazole derivatives having herbicidal activity, their preparation and their use SANKYO CO (JP) 1997-11-05 EP disclosed
US-5424279-A Useful for rice crops SANKYO COMPANY, LIMITED (JP) 1995-06-13 US disclosed
EP-0493925-A1 Pyrazole derivatives having herbicidal activity, their preparation and their use Sankyo Company Limited (JP) 1992-07-08 EP disclosed