Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782632 | 0.84 | ALDH1A1 (0.38) | NPC1RAB9AGPBAR1MEN1ALDH1A1 | |
| SCHEMBL8783288 | 0.82 | SCN4A (0.36) | TSHRMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL8782578 | 0.82 | PDE4A (0.36) | SIRT2TSHRNPC1RAB9AGPBAR1 | |
| SCHEMBL8783890 | 0.79 | CNR1 (0.36) | GPBAR1MEN1KMT2AMAPTHTR6 | |
| SCHEMBL8782648 | 0.79 | HTR3E (0.39) | GPBAR1MEN1KMT2AHTTLMNA | |
| SCHEMBL8782580 | 0.78 | HTR6 (0.34) | TSHRALDH1A1LMNAHTR6CNR1 | |
| SCHEMBL8782864 | 0.78 | HSD17B1 (0.35) | GPBAR1MEN1ALDH1A1KMT2ACNR1 | |
| SCHEMBL9260183 | 0.77 | LMNA (0.41) | TSHRGPBAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL8782628 | 0.77 | ALDH1A1 (0.35) | TSHRALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL8782433 | 0.76 | GPBAR1 (0.35) | SIRT2RAB9AGPBAR1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493925-B1 | Pyrazole derivatives having herbicidal activity, their preparation and their use | SANKYO CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5424279-A | Useful for rice crops | SANKYO COMPANY, LIMITED (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0493925-A1 | Pyrazole derivatives having herbicidal activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-07-08 | — | — | EP | disclosed |