Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646966 | 0.83 | CA2 (0.46) | PSMD10CA2MTNR1AMTNR1B | |
| SCHEMBL8650329 | 0.83 | MTNR1A (0.46) | PSMD10CA2MTNR1AMTNR1B | |
| SCHEMBL8650374 | 0.82 | CA2 (0.41) | CA2KIF11MTNR1AMTNR1BHRH3 | |
| SCHEMBL8645804 | 0.80 | SMN1; SMN2 (0.44) | PSMD10CA2MTNR1A | |
| SCHEMBL18165202 | 0.75 | PSMD10 (0.41) | PSMD10STAT3ALDH1A1 | |
| SCHEMBL8788477 | 0.74 | MTNR1A (0.38) | KIF11MTNR1AMTNR1BHRH3 | |
| SCHEMBL8649697 | 0.73 | SMN1; SMN2 (0.46) | CA2MTNR1A | |
| SCHEMBL201311 | 0.70 | PRSS1 (0.48) | — | |
| SCHEMBL9709447 | 0.69 | ALDH1A1 (0.51) | PSMD10CA2STAT3ALDH1A1 | |
| SCHEMBL18926552 | 0.69 | PSMD10 (0.45) | PSMD10STAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761666-A2 | Antidepressant 1-arylalkyl-4-(alkoxypyridinyl)- or 4-(alkoxypyrimidinyl)piperazine derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-03-12 | — | — | EP | disclosed |