Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787265 | 0.95 | CCR6 (0.42) | NR1D1PPARGDRD4ALDH1A1KDM4E | |
| SCHEMBL8053562 | 0.86 | HPGD (0.42) | ALDH1A1HPGDNPC1CCR6PAX8 | |
| SCHEMBL8787114 | 0.85 | ALDH1A1 (0.41) | PPARGDRD4ALDH1A1HPGDNPC1 | |
| SCHEMBL8047896 | 0.82 | NPC1 (0.45) | ALDH1A1NPC1CCR6PAX8 | |
| SCHEMBL8053341 | 0.82 | RAB9A (0.47) | KDM4EHPGDNPC1LMNA | |
| SCHEMBL8787321 | 0.81 | APP (0.43) | PPARGDRD4ALDH1A1HPGDDRD2 | |
| SCHEMBL8787183 | 0.81 | DRD3 (0.41) | NR1D1PPARGDRD4ALDH1A1KDM4E | |
| SCHEMBL8046943 | 0.81 | CCR6 (0.47) | HPGDNPC1CCR6PAX8 | |
| SCHEMBL8652547 | 0.79 | NR1D1 (0.38) | NR1D1ALDH1A1CCR5CCR6PAX8 | |
| SCHEMBL8653424 | 0.78 | CCR6 (0.39) | NR1D1ALDH1A1KDM4ECCR5CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769496-A1 | NOVEL 2,3-DIHYDROBENZOFURAN DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-04-23 | — | — | EP | disclosed |