Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 10/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053562 | 0.94 | HPGD (0.42) | CCR6PAX8NPC1RAB9ASIGMAR1 | |
| SCHEMBL8050607 | 0.94 | SIGMAR1 (0.50) | CCR6PAX8NPC1RAB9ASIGMAR1 | |
| SCHEMBL8047896 | 0.88 | NPC1 (0.45) | CCR6PAX8NPC1RAB9ASIGMAR1 | |
| SCHEMBL8787265 | 0.87 | CCR6 (0.42) | CCR6PAX8SIGMAR1TMEM97HPGD | |
| SCHEMBL8053341 | 0.86 | RAB9A (0.47) | NPC1RAB9ASIGMAR1HPGDSMN1; SMN2 | |
| SCHEMBL8035914 | 0.84 | HDAC1 (0.41) | NPC1RAB9ASIGMAR1TMEM97HPGD | |
| SCHEMBL8053417 | 0.83 | SIGMAR1 (0.47) | NPC1RAB9ASIGMAR1TMEM97ACKR3 | |
| SCHEMBL8036154 | 0.83 | SIGMAR1 (0.47) | NPC1RAB9ASIGMAR1TMEM97HPGD | |
| SCHEMBL8788877 | 0.81 | NR1D1 (0.39) | CCR6PAX8NPC1HPGD | |
| SCHEMBL8045249 | 0.80 | TMEM97 (0.48) | NPC1RAB9ASIGMAR1TMEM97HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0679649-A1 | 2,3-DIHYDROBENZOFURAN DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-11-02 | — | — | EP | disclosed |