Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053562 | 0.91 | HPGD (0.42) | RAB9ANPC1HPGDSIGMAR1SMN1; SMN2 | |
| SCHEMBL8046943 | 0.86 | CCR6 (0.47) | RAB9ANPC1HPGDSIGMAR1SMN1; SMN2 | |
| SCHEMBL8047896 | 0.85 | NPC1 (0.45) | RAB9ANPC1SIGMAR1SMN1; SMN2KMT2A | |
| SCHEMBL8047459 | 0.85 | NPC1 (0.49) | RAB9ANPC1CTDSP1TDP1OPRK1 | |
| SCHEMBL8788877 | 0.82 | NR1D1 (0.39) | NPC1HPGDKDM4ELMNA | |
| SCHEMBL8050607 | 0.80 | SIGMAR1 (0.50) | RAB9ANPC1SIGMAR1 | |
| SCHEMBL8787265 | 0.77 | CCR6 (0.42) | HPGDKDM4ESIGMAR1 | |
| SCHEMBL8045655 | 0.77 | HPGD (0.48) | RAB9ANPC1OPRK1HPGDHSD17B10 | |
| SCHEMBL8035576 | 0.75 | HPGD (0.47) | RAB9ANPC1OPRK1HPGDHSD17B10 | |
| SCHEMBL8048207 | 0.75 | SIGMAR1 (0.45) | RAB9ANPC1OPRK1HPGDSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0679649-A1 | 2,3-DIHYDROBENZOFURAN DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-11-02 | — | — | EP | disclosed |