Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788897 | 0.78 | SHMT2 (0.35) | SHMT2DHFRFFAR1LMNAL3MBTL1 | |
| SCHEMBL6979088 | 0.72 | ITGB3 (0.39) | ITGB3 | |
| SCHEMBL15669253 | 0.66 | ADRA2C (0.51) | SHMT2CYP2C19POLBADRA2CFFAR1 | |
| SCHEMBL30950069 | 0.66 | TBXA2R (0.38) | DHFRKMT2AALDH1A1 | |
| SCHEMBL7123402 | 0.65 | GABRP (0.38) | SHMT2FFAR1HSD17B10L3MBTL1CA1 | |
| Propionic Acid SCHEMBL28016400 | 0.64 | ALOX15 (0.39) | KMT2AMEN1 | |
| SCHEMBL13180243 | 0.62 | RIOK2 (0.60) | KMT2AMEN1 | |
| SCHEMBL15527710 | 0.62 | GABRP (0.46) | KMT2ALMNAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL24364300 | 0.61 | NOS2 (0.47) | SHMT2 | |
| SCHEMBL21254534 | 0.61 | CA1 (0.40) | ITGB3ITGAVADRA2CHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804418-A2 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | disclosed |