Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736838 | 0.90 | MAPT (0.48) | MAPTKDM4EGRM5TP53POLB | |
| SCHEMBL10067206 | 0.85 | TAS2R14 (0.39) | MAPTKDM4EGRM5MRGPRX4TP53 | |
| SCHEMBL879552 | 0.81 | SMN1; SMN2 (0.43) | POLBMEN1CYP3A4CYP2C19KMT2A | |
| SCHEMBL879553 | 0.81 | MAPT (0.47) | MAPTKDM4EGRM5MRGPRX4JAK2 | |
| SCHEMBL13543374 | 0.80 | RAB9A (0.42) | MAPTKDM4EHCRTR1HCRTR2MEN1 | |
| SCHEMBL17681643 | 0.80 | MAPT (0.50) | MAPTKDM4EGRM5TP53HCRTR1 | |
| SCHEMBL13753890 | 0.77 | JAK2 (0.57) | MRGPRX4CYP2D6JAK2JAK1TYK2 | |
| SCHEMBL2736489 | 0.75 | ALDH1A1 (0.43) | TP53POLBCYP2D6MEN1KMT2A | |
| SCHEMBL2736852 | 0.75 | ALDH1A1 (0.50) | TP53POLBNPSR1LMNASMN1; SMN2 | |
| SCHEMBL10067207 | 0.75 | ALDH1A1 (0.48) | MAPTKDM4ETP53POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9677053-B2 | Laccases for bio-bleaching | BASF ENZYMES LLC (US) | 2017-06-13 | — | — | US | disclosed |
| US-9677053-B2 | Laccases for bio-bleaching | BASF ENZYMES LLC (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160237411-A1 | LACCASES FOR BIO-BLEACHING | VERENIUM CORPORATION | 2016-08-18 | — | — | US | disclosed |
| US-20160237411-A1 | LACCASES FOR BIO-BLEACHING | VERENIUM CORPORATION | 2016-08-18 | — | — | US | disclosed |
| US-9353477-B2 | Laccases for bio-bleaching | BASF ENZYMES LLC (US) | 2016-05-31 | — | — | US | disclosed |
| US-9353477-B2 | Laccases for bio-bleaching | BASF ENZYMES LLC (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2434008-B1 | Laccases for pulp bio-bleaching | BASF ENZYMES LLC (US) | 2015-07-08 | — | — | EP | disclosed |
| US-20150125936-A1 | LACCASES FOR BIO-BLEACHING | BASF SE (DE) | 2015-05-07 | — | — | US | disclosed |
| US-20150125936-A1 | LACCASES FOR BIO-BLEACHING | BASF SE (DE) | 2015-05-07 | — | — | US | disclosed |
| US-8951766-B2 | Laccases for bio-bleaching | BASF ENZYMES LLC (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951766-B2 | Laccases for bio-bleaching | BASF ENZYMES LLC (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130126110-A1 | LACCASES FOR BIO-BLEACHING | BASF SE (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20130126110-A1 | LACCASES FOR BIO-BLEACHING | BASF SE (DE) | 2013-05-23 | — | — | US | disclosed |
| US-8377670-B2 | Laccases for bio-bleaching | VERENIUM CORPORATION (US) | 2013-02-19 | — | — | US | disclosed |
| US-8377670-B2 | Laccases for bio-bleaching | VERENIUM CORPORATION (US) | 2013-02-19 | — | — | US | disclosed |
| EP-2434008-A1 | Laccases for pulp bio-bleaching | Verenium Corporation (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2059587-B1 | LACCASES FOR PULP BIO-BLEACHING | VERENIUM CORP (US) | 2012-01-04 | — | — | EP | disclosed |
| US-20100018658-A1 | Laccases for Bio-Bleaching | VERENIUM CORPORATION (US) | 2010-01-28 | — | — | US | disclosed |
| US-20100018658-A1 | Laccases for Bio-Bleaching | VERENIUM CORPORATION (US) | 2010-01-28 | — | — | US | disclosed |
| WO-2008027501-A2 | LACCASES FOR PULP BIO-BLEACHING | VERENIUM CORPORATION (US) | 2008-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100018658-A1 | Laccases for Bio-Bleaching | AOX1, GUSB, LPO | MAPT 1646/4885KDM4E 1409/4885GRM5 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.