Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797671 | 0.87 | ALDH1A1 (0.52) | ALDH1A1ALOX15POLBNPSR1FPR2 | |
| SCHEMBL8706568 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ALOX15POLBNPSR1CYP3A4 | |
| SCHEMBL8702761 | 0.77 | LPAR1 (0.39) | POLBNPSR1MAPTLPAR1 | |
| SCHEMBL8798636 | 0.74 | KDM4E (0.51) | ALDH1A1 | |
| SCHEMBL20397870 | 0.70 | FPR2 (0.64) | POLBROCK2ROCK1FPR2ADRB1 | |
| SCHEMBL8797685 | 0.70 | HDAC1 (0.34) | ALDH1A1POLBROCK2LPAR1 | |
| SCHEMBL8801653 | 0.69 | LPAR1 (0.34) | LPAR1 | |
| SCHEMBL20397713 | 0.69 | TAS1R3 (0.55) | ALDH1A1ALOX15POLBCYP3A4MAPK1 | |
| SCHEMBL31611727 | 0.68 | ROCK2 (0.55) | ALDH1A1NPSR1CYP3A4MAPK1ROCK2 | |
| SCHEMBL8804341 | 0.67 | LMNA (0.34) | ALOX15POLBNPSR1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |