Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.49 |
| ▸ | FNTB | P49356 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799600 | 0.96 | HPGD (0.48) | HPGDALDH1A1LMNANPSR1HTT | |
| SCHEMBL7811262 | 0.95 | FNTA (0.53) | FNTAFNTBHPGDALDH1A1LMNA | |
| SCHEMBL8799604 | 0.81 | FNTA (0.42) | FNTAFNTBHPGDALDH1A1LMNA | |
| SCHEMBL8798403 | 0.80 | PRKCZ (0.48) | FNTAFNTBALDH1A1LMNAHTT | |
| SCHEMBL657182 | 0.80 | PRKCZ (0.48) | FNTAFNTBALDH1A1LMNAHTT | |
| SCHEMBL12268167 | 0.78 | FNTA (0.47) | FNTAFNTBALDH1A1LMNAHTT | |
| SCHEMBL7812248 | 0.77 | MTNR1A (0.49) | FNTAFNTBHPGDHTT | |
| SCHEMBL7807756 | 0.77 | FNTA (0.69) | FNTAFNTBHPGDALDH1A1MEN1 | |
| SCHEMBL2471681 | 0.73 | GAA (0.56) | ALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL692174 | 0.72 | LMNA (0.49) | ALDH1A1LMNAHTTMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773929-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996039386-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |