Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084596 | 0.90 | IDO1 (0.33) | IDO1TDP1PDE4DPDE4BKMT2A | |
| SCHEMBL6967360 | 0.86 | IDO1 (0.36) | IDO1TDP1PDE4DPDE4BKMT2A | |
| SCHEMBL7079909 | 0.86 | IDO1 (0.36) | IDO1TDP1PDE4DPDE4BKMT2A | |
| SCHEMBL7081541 | 0.86 | IDO1 (0.35) | IDO1TDP1KMT2APOLBMEN1 | |
| SCHEMBL6973001 | 0.86 | P2RX3 (0.33) | IDO1TDP1KMT2AL3MBTL1TP53 | |
| SCHEMBL6960281 | 0.85 | PIM1 (0.36) | IDO1TDP1KMT2APOLBL3MBTL1 | |
| SCHEMBL6968857 | 0.85 | PIM1 (0.33) | IDO1TDP1KMT2AGRM5L3MBTL1 | |
| SCHEMBL6974703 | 0.85 | TDP1 (0.41) | TDP1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL6972144 | 0.84 | IDO1 (0.35) | IDO1TDP1PDE4DPDE4BKMT2A | |
| SCHEMBL6974232 | 0.84 | IDO1 (0.35) | IDO1TDP1PDE4DPDE4BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |