Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972404 | 0.82 | VCP (0.36) | VCPTP53 | |
| SCHEMBL6960433 | 0.80 | TDP1 (0.34) | VCPTP53 | |
| SCHEMBL6966496 | 0.80 | VCP (0.37) | VCPTP53 | |
| SCHEMBL6969238 | 0.79 | VCP (0.38) | VCP | |
| SCHEMBL14439828 | 0.79 | TDP1 (0.40) | VCPTP53MDM2 | |
| SCHEMBL14439830 | 0.77 | TP53 (0.39) | VCPTP53 | |
| SCHEMBL6967249 | 0.77 | HSP90B1 (0.33) | VCP | |
| SCHEMBL14439841 | 0.77 | VCP (0.36) | VCPTP53 | |
| SCHEMBL14439829 | 0.77 | VCP (0.36) | VCPTP53 | |
| SCHEMBL6965896 | 0.77 | VCP (0.36) | VCPTP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |