Sarcosine

Sarcosine

SCHEMBL8800845

CC1(C)C2CCC1(CS(=O)(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(=O)C2.CNCC(=O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 4/20 0.49
ITGAV P06756 4/20 0.49
F10 P00742 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
F2 P00734 2/20 0.44
PRSS1 P07477 2/20 0.44
PRSS2 P07478 2/20 0.44
PRSS3 P35030 2/20 0.44
ALDH1A1 P00352 2/20 0.43
CA1 P00915 8/20 0.42
CA2 P00918 8/20 0.42
CA5A P35218 8/20 0.42
CA5B Q9Y2D0 8/20 0.42
ITGA2B P08514 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL7359600 0.96 ITGB3 (0.47) ITGB3ITGAVF10CYP1A2CYP2C19
Arginine SCHEMBL7363181 0.91 ITGB3 (0.43) ITGB3ITGAVF10CYP1A2CYP2C19
Arginine SCHEMBL7360830 0.87 CYP1A2 (0.43) F10CYP1A2CYP2C19F2PRSS1
Sarcosine SCHEMBL7364548 0.84 ITGB3 (0.50) ITGB3ITGAVF10CYP1A2CYP2C19
SCHEMBL16026981 0.80 ITGB3 (0.59) ITGB3ITGAVF10CYP1A2CYP2C19
SCHEMBL16026979 0.80 ITGB3 (0.59) ITGB3ITGAVF10CYP1A2CYP2C19
Arginine SCHEMBL28791955 0.78 F2 (0.47) CYP1A2CYP2C19F2PRSS1PRSS2
SCHEMBL6975926 0.77 ALDH1A1 (0.57) ITGB3ITGAVF10CYP1A2CYP2C19
SCHEMBL7355659 0.77 ITGB3 (0.55) ITGB3ITGAVF10CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL7943485 0.76 ALDH1A1 (0.56) ITGB3ITGAVF10CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0801654-A1 N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa CORVAS INTERNATIONAL, INC. (US) 1997-10-22 EP disclosed