Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 11/20 | 0.51 |
| ▸ | CCKAR | P32238 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800433 | 0.90 | CCKBR (0.46) | CCKBRCCKAR | |
| SCHEMBL8801355 | 0.82 | HTT (0.43) | CCKBRCCKARHTTMAPTTSHR | |
| SCHEMBL8804138 | 0.81 | CCKBR (0.42) | CCKBRCCKAR | |
| SCHEMBL8801349 | 0.75 | HTT (0.45) | CCKBRCCKARHTTMAPTTSHR | |
| SCHEMBL8537024 | 0.75 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL8537020 | 0.75 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL8669318 | 0.74 | CHRM1 (0.53) | CCKBRCCKAR | |
| SCHEMBL8804134 | 0.73 | CCKBR (0.41) | CCKBRCCKARMAPT | |
| SCHEMBL8800940 | 0.73 | CCKBR (0.64) | CCKBRCCKARMAPT | |
| SCHEMBL11118972 | 0.73 | NFKB1 (0.46) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |