Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.42 |
| ▸ | CCKAR | P32238 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801216 | 0.92 | CCKBR (0.39) | CCKBRCCKARALOX15HSD17B10OPRK1 | |
| SCHEMBL8801767 | 0.90 | BRD4 (0.41) | CCKBRALOX15HSD17B10TP53OPRK1 | |
| SCHEMBL8800433 | 0.88 | CCKBR (0.46) | CCKBRCCKARALOX15HSD17B10CHRM1 | |
| SCHEMBL8669229 | 0.83 | CCKBR (0.57) | CCKBRCCKAR | |
| SCHEMBL8801355 | 0.83 | HTT (0.43) | CCKBRCCKAR | |
| SCHEMBL8804134 | 0.81 | CCKBR (0.41) | CCKBRCCKARALOX15HSD17B10CHRM1 | |
| SCHEMBL8801124 | 0.81 | CCKBR (0.51) | CCKBRCCKAR | |
| SCHEMBL8803196 | 0.76 | CCKBR (0.47) | CCKBRCCKAROPRK1KCNH2 | |
| SCHEMBL8667990 | 0.76 | CCKBR (0.55) | CCKBRCCKAROPRK1KCNH2 | |
| SCHEMBL8800940 | 0.74 | CCKBR (0.64) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |