Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877192 | 0.91 | GRIN2B (0.36) | KAT2BMCHR1ADRA2AADRA2BADRA2C | |
| SCHEMBL7014109 | 0.90 | ADRA2A (0.32) | MCHR1ADRA2AADRA2BADRA2C | |
| SCHEMBL9138352 | 0.89 | BACE1 (0.37) | CARM1PRMT6KAT2BADRA2AADRA2B | |
| SCHEMBL9139815 | 0.89 | PTGS2 (0.34) | KAT2BMCHR1ADRA2AADRA2BADRA2C | |
| SCHEMBL8186216 | 0.86 | SLC6A4 (0.36) | KAT2BKCNH2 | |
| SCHEMBL8804858 | 0.83 | CYP2D6 (0.36) | KAT2BMCHR1ADRA2AADRA2BADRA2C | |
| SCHEMBL8177078 | 0.83 | ADRA1A (0.35) | KAT2BADRA2AADRA2BADRA2CKCNH2 | |
| SCHEMBL8803882 | 0.83 | USP2 (0.35) | CHRNA7ADRA2AADRA2BADRA2CKCNH2 | |
| SCHEMBL8804496 | 0.82 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CACHEDRD2 | |
| SCHEMBL8804812 | 0.82 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CACHEDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647231-B1 | N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS, ETC. | BASF AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |