Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879255 | 0.91 | P2RX3 (0.37) | KAT2BP2RX3ADRA2AADRA2BADRA2C | |
| SCHEMBL8804674 | 0.91 | CARM1 (0.34) | KAT2BMCHR1ADRA2AADRA2BADRA2C | |
| SCHEMBL8876991 | 0.86 | MAPT (0.37) | GRIN2BKAT2BOPRM1KMT2AADRA2A | |
| SCHEMBL8877896 | 0.84 | KAT2B (0.33) | KAT2BMCHR1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL8877213 | 0.84 | KAT2B (0.32) | KAT2BP2RX3PTGS2LMNAALDH1A1 | |
| SCHEMBL7014109 | 0.81 | ADRA2A (0.32) | MCHR1ADRA2AADRA2BADRA2CPTGS2 | |
| SCHEMBL8804496 | 0.81 | ADRA2A (0.50) | KMT2AADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL9138352 | 0.80 | BACE1 (0.37) | KAT2BBACE1KMT2AADRA2AADRA2B | |
| SCHEMBL9139815 | 0.80 | PTGS2 (0.34) | KAT2BMCHR1ADRA2AADRA2BADRA2C | |
| SCHEMBL8186216 | 0.79 | SLC6A4 (0.36) | KAT2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616705-A | N-substituted azabicycloheptane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |